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A Review on the Sex Differences in Organ and System Pathology with Alcohol Drinking

[ Vol. 9 , Issue. 2 ]

Author(s):

Vatsalya Vatsalya, Hammad Bin Liaquat, Kuldeep Ghosh, Sri Prakash Mokshagundam and Craig J McClain   Pages 87 - 92 ( 6 )

Abstract:


Hazardous consequences of alcohol consumption adversely influence overall health, specifically physical and mental health. Differences in alcohol consumption and manifestations in pathology have been observed between males and females, however research on understanding these differences is limited. Negative consequences of alcohol consumption have now been studied including sex as a significant factor. Some studies have shown differences in the severity of consequences of alcohol consumption between the sexes, both in the mental consequences and changes/ injury in various organ systems. Over time, reports in females on both the dynamics of drinking and on the hazardous consequences of alcohol consumption have grown, primarily because of more awareness, better observation, and the inclusion of sex as a factor in scientific investigations. This paper reviews role of sex differences in pathophysiological and behavioral consequences of alcohol drinking.

Keywords:

Alcohol, organ injury, pharmacology, sex difference, pathology, addiction.

Affiliation:

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Louisville, Louisville, KY 40202, Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Louisville, Louisville, KY 40202, Division of Infectious Diseases, Department of Medicine, University of Louisville, Louisville, KY 40202, Division of Endocrinology, Department of Medicine, University of Louisville, Louisville, KY 40202, Department of Medicine, Pharmacology and Toxicology, University of Louisville School of Medicine, 505 S. Hancock St. CTR Room 503, Louisville KY 40202



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